Genesis 1:27
So God created man in his own image, in the image of God created he him; male and female created he them.

Genesis 2:23-24
23  And Adam said, This is now bone of my bones, and flesh of my flesh: she shall be called Woman, because she was taken out of Man.
24  Therefore shall a man leave his father and his mother, and shall cleave unto his wife: and they shall be one flesh.

Genesis 1:28
And God blessed them, and God said unto them, Be fruitful, and multiply, and replenish the earth, and subdue it:

Matthew 19:6
Wherefore they are no more twain, but one flesh. What therefore God hath joined together, let not man put asunder.